When I first started stamping I would make them all the same. Then I got bored with that and started making 2 different designs. That was problematic for me because then I had to decide which one to send to which person. I did that for a few years, then I decided I just didn't want to make them at all - it added too much to the already busy schedule.
Then I missed making Christmas cards because I would see so many beautiful ones in the gallery, so I started making "one (or two) of a kind" here and there whenever the mood struck. By Christmas I had enough to send out (I only send about 30), but I still had to get over the "hump" of deciding who received which card.
So, I've been all over the board. I know that probably doesn't help you at all, but that's been my journey!